Recent research suggests that the collection of saliva sample may improve the Covid 19 detection process. That can be done to eliminate the chance of nasopharyngeal testing and felicitate mass surveillance.
It is an innovative protocol that processes saliva samples with a bead mill homogenizer before real-time PCR (RT-PCR) testing results in higher sensitivity compared to NPS samples.
An experiment was conducted in several phases by collecting 240 matched NPS and saliva sample pairs to test SARS-CoV-2 RNA by RT-PCR.
Ravindra Kolhe, one of the members of the research team, said that the test is a game-changer in the process of fight against the pandemic. It has helped test mass population with a decreased exposure risk to the healthcare workers during the sample collection process.
An experiment was conducted in several phases by collecting 240 matched NPS and saliva sample pairs to test for SARS-CoV-2 RNA by RT-PCR. An additional study was conducted with samples with both protocol U and SalivaAl to determine if bead homogenization would affect the clinical sensitivity in NPS samples.
The test concluded that the detection rate was higher in saliva as compared to NPS samples.