Men who suffer from a low level of testosterone may be more prone to severe Covid-19 infections, say researchers.
According to a research carried out at a laboratory in New York stated that the lowest level of testosterone in the blood was at the highest risk of going on a ventilator, needing intensive care or dying.
Abhinav Diwan, who was one of the researchers at the Washington University School of medicine said that if a man had low testosterone during the time of admission at the hospital, his risk of having severe complication including fatal might increase as compared to the one who has more circulating testosterone.
In addition, it was found that lower testosterone levels in men also correlated with higher levels of inflammation and an increase in the activation of genes that allow the body to carry out functions of circulating sex hormones inside the cells.Diwan further added that if testosterone levels drop further during hospitalization, the risk increases.
A test was carried out among various patients at a hospital and the conclusion was made that among women there was no correlation between levels of any hormone and disease severity unlike among the males whose testosterone levels directly linked with Covid-19 severity.
A blood testosterone level of 250 nanograms per deciliter or less is considered low testosterone in adult men.
At hospital admission, men with severe Covid-19 had average testosterone levels of 53 nonograms per deciliter; men with less severe disease had average levels of 151 nanograms per deciliter.
It was observed that by the third day, the average testosterone level of the most severely ill men was only 19 nanograms per deciliter.
In addition, it was found that lower testosterone levels in men also correlated with higher levels of inflammation and an increase in the activation of genes that allow the body to carry out functions of circulating sex hormones inside the cells.